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The World's Most Powerful Antioxidant Superfruit
WITH DELPHINOL®
PLUS
TM
SUPER MAQUI BERRY
Rich Chilean soils combined with a unique microclimate created by the Andes mountains and Humboldt current are also stressed by high levels of sun radiation and large variations in temperature.
Plants that grow under these conditions contain unique phytochemical profiles that are not found in any other place in the world. These plants contain 30%- 40% more health-bearing molecules than their counterparts cultivated in other regions.
The unique harvest process and bioprocessing methodology help to maintain the purity of both the plants and the fruits.
The climate improves the quality of the berries, which result in a higher concentration of antioxidants and delphinidins. Our special indigenous Maqui berries are carefully selected by hand and harvested by families of collectors from wild forests and fields in Chile who follow old traditions that have been preserved by centuries in the Mapuche Communities.
SOURCE: INTA : National Institution of Foods and Technology, CHILE
Climate of southern Chile is more conducive to nutrient dense Maqui berries
CHILE
SOUTH AMERICA
with Maqui Bright® and Lutein
1.
Maqui berry is a dark purple berry from the Patagonian region, in Chile and Argentina.
2.
Maqui berry grows as an evergreen tree that reaches about 3 to 4 meters high (9-13 ft.). The fruit is a delicious berry with a dry flavor, shiny, purple-black and about 4-5 mm in diameter, edible, and medicinal with a very strong pigment.
3.
Maqui berry is harvested wild in central and southern Chile.
4.
Maqui berries by nature are extraordinarily rich in flavonoid, molecules otherwise known as anthocyanins, in addition to a high concentration of phenolic compounds. A subcategory of these flavonoids are called delphinidins, which are responsible for the berry’s dark purple pigment.
MAQUI BERRY
비만 세포 억제? 미란다 커가 사랑한 젊음의 열매
MNL GROUP is a Chilean company dedicated to the research and development of characterized and standardized natural extracts for application in animal and human health, through the use of advanced methods of extraction conducted at the highest level.
MNL Group S.A. is a company created in December 2010 from a spin-off of CTI HEALTH in Chile (Consortium for Technology and Research for Health) based on the initiative of entrepreneurs and scientists who strive to generate standardized natural extracts from botanical origin, focused on nutraceutical, functional foods and botanical drugs markets.
MNL Group’s objective is to offer products with the highest quality and safety standards, that contribute to human and animal health, promoting natural components from botanical origin, with clinically proven effectiveness in the control and prevention of high impact worldwide diseases.
DELPHINOL® is a world class and unique extract that is produced by Anklam, a state-of-the-art research facility located in Germany. The lab ensures that production is GMP (Good Manufacturing Procedures) compliant, which also ensures the consistent quality and safety of the products. The method used for DELPHINOL® production is patent protected under the MNL Group (US 14/067,066).
Anklam Extrakt has been granted GMP an HACCP certification by the German inspection body, as well as a Kosher certification by Orthodox Union, NY and a Halal certificate by Halal Control and an EU Organic certification.
HOW SUPER MAQUI™ WITH DELPHINOL® IS MADE
The Super Maqui™ berries we sourced grow in a unique microclimate in the Andes Mountains. Plants that grow in these conditions contain 30%- 40% more health-bearing molecules than their counterparts cultivated in other regions.
Harvested in the wild in central and southern Chile
Super Maqui™ berries are carefully selected by hand and put directly into -25°C containers to preserve their polyphenol content. This is done by families of collectors from wild forests in Chile who follow traditions preserved in the Mapuche Communities.
DELPHINOL® is produced by Anklam in Germany using a patented process in coherence with GMP (Good Manufacture Procedures).
It’s then put into capsules and packaged right in Canada.
THE SUPER MAQUI BERRY
THE MOST POTENT ANTIOXIDANT SUPERFRUIT IN THE WORLD
The Super Maqui™ berry is considered to be the most powerful antioxidant superfruit for being rich in polyphenols, anthocyanins, and delphinidins. These components neutralize free radicals, which are agents that are highly reactive and can cause oxidative stress and inflammation in the body.
The Super Maqui™ berry is grown in the wild Chilean forest in a challenging environment which includes high levels of sun radiation and large variations in temperature. These conditions as well as other environmental factors have yielded a berry with the highest ORAC value of any fruit or berry tested.
Source: ORAC (Oxygen Radical Absorbance Capacity) Database of the US Department of Agriculture of the USA. May, 2010.
ANTIOXIDANT
SUPER MAQUI PLUS™ WITH DELPHINOL® - SUPERIOR FULL-SPECTRUM ANTIOXIDANT ORAC POTENCY
Super Maqui Plus™ with Delphinol® has been analyzed at the Brunswick Laboratories for an estimation of the total ORAC value.
Super Maqui Plus™ with Delphinol® shows superior quenching efficacy for all five reactive oxygen radical species and yields a total ORAC potency of 30,852 micro-mol Trolox equivalents per gram of the extract.
Out of all anthocyanins, delphinidins are the most effective at neutralizing free radicals, which is what sets Delphinol® apart from any other Maqui Berry extract.
Ou et al., Brunswick Laboratories certificate of analysis , 2013.
OXIDATIVE STRESS
INFLAMMATION
PREVENTS
INFLAMMATION
OXIDATIVE STRESS
ANTHOCYANINS
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ANTI-AGING
GLOW TOGETHER
Free radicals, oxidative stress, and inflammation all play a huge part in visible aging. Super Maqui Plus™ with Delphinol® helps reverse and prevent symptoms related to visible aging.
• A 2015 study published by Minerva Cardioangiologica found that after using Delphinol®, the skin was protected from photodamage caused by UVA/UVB radiation.
• The low molecular weight of Super Maqui Plus™ with Delphinol® makes it easier to integrate into the bloodstream quicker to manage inflammation and protect fibroblasts in the dermis – this dictates the skin’s collagen production, elasticity, and wrinkling.
ANTI-INFLAMMATORY
EXPERIENCE ALL THE NATURAL ANTI-INFLAMMATORY BENEFITS
Oxidative stress caused by free radicals, which can trigger pro-inflammatory responses in the body and can lead to various diseases and visible aging, is minimized with the implementation of Super Maqui Plus™ with Delphinol®.
The transcription factor nuclear factor-kB (NF-kB) is activated by oxidative stress and pro-inflammatory stimuli and controls the expression of numerous genes involved in the inflammatory response.
Dampening NF-kB activation limits the inflammatory response, which has been suggested as a potential strategy to prevent chronic inflammatory diseases.
CARDIOVASCULAR
LOWERS OXIDIZED LDL LEVELS
A third study aimed to test Super Maqui Plus™ with Delphinol®’s effectiveness over a 90 day period. They found that the antioxidant capacity of the extract helped lower oxidized LDL levels increasingly over 90 days, achieving statistical significance after just 60 days of consistent use.
The study also looked at other cardiovascular benefits of Super Maqui Plus™ with Delphinol®. This included seeing a significant drop in total and low-density (LDL) cholesterol and an increase in high-density (HDL) cholesterol after 90 days.
SUGAR METABOLISM
ENJOY AN ACTIVE, EFFICIENT, AND STABLE METABOLISM
The delphinidins of Super Maqui Plus™ with Delphinol® have powerful anti inflammatory effects due to their activation of the PPAR gamma receptor. This activation mechanism is strongly correlated with the control of Type 2 diabetes since it enhances insulin sensitivity.
Studies showed Super Maqui Plus™ with Delphinol® dose dependently lowered both glucose and insulin levels in pre-diabetic participants with the most impactful doses ranging from 60-120 mg.
Antioxidants for the Maintenance of Eye Health
WITH MAQUIBRIGHT® & LUTEIN
EYE HEALTH
TM
For Vision Health
MAQUIBRIGHT® is the standardized extract of Maqui (botanical name Aristotelia chilensis) berries produced by Anklam, a unique oral supplement that supports eye health from the inside out for systemic and continuous comfort. The method used for MAQUIBRIGHT® production is patent protected under the MNL Group (US 14/067,066).
Anklam Extrakt has been granted GMP an HACCP certification by the German inspection body, as well as a Kosher certification by Orthodox Union, NY and a Halal certificate by Halal Control and an EU Organic certification.
HOW SUPER MAQUI EYE HEALTH™ WITH MAQUIBRIGHT® IS MADE
The Super Maqui™ berries we sourced grow in a unique microclimate in the Andes Mountains. Plants that grow in these conditions contain 30%- 40% more health-bearing molecules than their counterparts cultivated in other regions.
Harvested in the wild in central and southern Chile
Super Maqui™ berries are carefully selected by hand and put directly into -25°C containers to preserve their polyphenol content. This is done by families of collectors from wild forests in Chile who follow traditions preserved in the Mapuche Communities.
MAQUIBRIGHT® is produced by Anklam in Germany using a patented process in coherence with GMP (Good Manufacture Procedures).
It’s then put into capsules and packaged right in Canada.
MaquiBright ®
• Helps to maintain eyesight in conditions (associated with sunlight
damage), such as cataracts and age-related macular degeneration.
• Helps to reduce the risk of cataracts.
• Helps to improve macular pigment density.
• Provides antioxidants for the maintenance of eye health.
• Provides antioxidant(s) that help(s) protect (cell) against (the cell
damage caused by) free radicals.
• Has been shown to alleviate eye dryness and increases tear production.
MaquiBright ®
has been clinically proven to contain phytochemical compounds (anthocyanins) known as delphinidins that have powerful eye-protective actions, and proves to be most bioavailable by lacrimal gland cells, therefore most naturally effective to combat dry eyes.
TM
MaquiBright ®
has been clinically proven to reduce oxidative stress. Abrogation of oxidative stress can help to resist the developments of many eye diseases, including corneal inflammation, cataracts, uveitis, and age related retinal and macular degeneration.
DRY EYES
RESTORES FLUID RELEASE FROM LACRIMAL GLANDS
• Dry eye syndrome, resulting from insufficient tear fluid generation to keep eyes moist, is very common and age related, most especially in mature women, leading to sensitive, stinging, itching eyes and can lead to ocular and tear glands damage. 1-4
• The term “tear film breakup time” is used to describe how rapidly the normal smooth tear layer disperses.4-6 When the tear film breakup time is less than the rate of blinking, it creates intermittent periods of exposure to dryness and potential irritants, leading to the symptoms of dry eye syndrome.
• When dry eye syndrome was untreated or inadequately treated, it could lead to damage to the thin outermost region over the lens known as the cornea and the lubricating cell layer that lines the eyeball and inner surfaces of the lids called conjunctiva.4 Even an injury as small as a slight scratch on the surface of the eye doesn’t heal as well when the eye is dry.7
• Latest discoveries have shown that the protective plant compounds extracted from the wild grown South American Maqui Berry (Aristotelia chilensis) can reduce light-induced damage to the eye tissues and effectively enhance normal tear output.
• Numerous scientific studies have demonstrated how Maqui Berry Extract utilizes the body’s own natural mechanisms to boost tear production.
• When Maqui Berry Extract was tested in human volunteers with dry eye syndrome, it was found that a dose of 60 mg per day of the extract improved dry eye syndrome from the 30th day of use.8
EYE HEALTH
SPECIFIC DELPHINIDIN IS THE ACTIVE PRINCIPAL
• Maqui Berries, growing in the Patagonia region of Chile, has been used as a traditional medicine to provide powerful eye-protective benefits since ancient times.
• MaquiBright®, a Maqui Berry extract with a standardized content of anthocyanins (35% NLT) and an astonishing level of delphinidins (25% NLT), the highest among all food ingredient currently available, is known to inhibit the production of reactive oxygen species (ROS) in the lacrimal gland tissue and known to suppress corneal damage as well as lacrimal gland tissue dysfunction.
• MaquiBright® demonstrates a notable benefit of reducing symptoms of eye fatigue and stiff shoulders.
• MaquiBright® shields ocular structures from high ultraviolet light and reactive oxygen species exposure, and alleviates bothersome ocular symptoms.
• MaquiBright® helps to reduce the risk of developing cataracts and age related macular degeneration, and helps to maintain eyesight in such conditions.
• MaquiBright® helps to improve macular pigment optical density.
• This Oral Therapy with MaquiBright® is now known to address the cause of dry eyes symptoms, with studies proving the use of it leads to continuous improvements in eye comfort. 8
• This scientific breakthrough now allows us to, most naturally and effectively; combat irritating dry eyes with an oral, once-a-day supplement of Super Maqui Eye Health™ with MaquiBright® & Lutein.
REFERENCE
1. Garcia-Resua C, Pena-Verdeal H, Remeseiro B, Giraldez MJ, Yebra-Pimentel E. Correlation between tear osmolarity and tear meniscus. Optom Vis Sci. 2014 Dec;91(12):1419-29.
2. Yazici A, Sari ES, SahinG, et al. Change in tear film characteristics in visual display terminal users. Eur J Ophthalmol. 2015 Feb 12;25(2):85-9.
3. Schaumberg DA, Sullivan DA, Buring JE, Dana MR. Prevalence of dry eye syndrome among US women. Am J Ophthalmol. 2003 Aug;136(2):318-26.
4. Gayton JL. Etiology, prevalence, and treatment of dry eye disease. Clin Ophthalmol. 2009;3:405-12.
5. Su TY, Chang SW, Yang CJ, Chiang HK. Direct observation and validation of fluorescein tear film break-up patterns by using a dual thermal-fluorescent imaging system. Biomed Opt Express. 2014 Jul 14;5(8):2614-9.
6. Bhargava R, Kumar P, Kumar M, Mehra N, Mishra A. A randomized controlled trial of omega-3 fatty acids in dry eye syndrome. Int J Ophthalmol. 2013;6(6):811-6.
7. Cho YK, Archer B, Ambati BK. Dry eye predisposes to corneal neovascularization and lymphangiogenesis after corneal injury in a murine model. Cornea. 2014 Jun;33(6):621-7.
8. Hitoe S, Tanaka J, Shimoda H. MaquiBright standardized maqui berry extract significantly increases tear fluid production and ameliorates dry eye-related symptoms in a clinical pilot trial. Panminerva Med. 2014 Sep;56(3 Suppl 1):1-6.
* Information herein is for reference only and is not intended to be taken as medical advice. No therapeutic or medical claims are either implied or made. Do not alter any medical treatment, or the use of medication without the permission of your medical care providers
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